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. Author manuscript; available in PMC: 2014 Oct 3.
Published in final edited form as: J Surg Res. 2013 Jan 1;184(2):730–738. doi: 10.1016/j.jss.2012.12.009

Figure 6. Epithelial cell destruction with addition of P2 bacteria in the ABM.

Figure 6

Putative mechanisms of P2 cytotoxicity were coded into the ABM. Both the secreted toxin (P2-SEC) and the injected cytotoxic (P2-INJ) mechanisms of P2 bacteria (green) lead to widespread epithelial cell death (white) and complete destruction of the simulated monolayer.