Table 1.
Variable | Lower SBP target (<130mm Hg) (n = 1,501) | Higher SBP target (130–149mm Hg) (n = 1,519) |
---|---|---|
Mean SBP ± SD at baseline | 142.4±18.5 | 143.6±19.1 |
Mean SBP ± SD at last follow-up** | 126.7±16.5 | 137.4±16.2 |
Mean SBP ± SD across quarterly follow-ups (excluding initial 6 months)** | 125.1±14.7 | 137.1±14.4 |
No. (%) in target at last follow-up | 1,034 (69.6) | 855 (56.9) |
Mean DBP ± SD at baseline* | 77.6±10.4 | 79.0±10.8 |
Mean DBP ± SD at last follow-up** | 69.1±10.4 | 74.8±10.9 |
Mean DBP ± SD across quarterly follow-ups (excluding initial 6 months)** | 68.5±9.9 | 75.0±10.3 |
SBP <140mm Hg, no. (%) | ||
Baseline | 722 (48.1) | 699 (46.0) |
Year 1 | 1,120 (84.1) | 776 (56.9) |
End of study | 1,100 (85.1) | 754 (57.7) |
Study Status, no. (%) | ||
Always active | 1,147 (76.4) | 1,126 (74.1) |
Ever inactive | 304 (20.3) | 331 (21.8) |
Ever failure to achieve assigned target | 50 (3.3) | 62 (4.1) |
Mean number of BP checks ± SD | 21.3±11.6 | 21.6±12.2 |
Antihypertensive medication adherence excellent or good at >75% of quarterly visits, no. (%) | 1,303 (90.7) | 1,248 (92.5) |
Side-effects possibly related to blood pressure management, no. (%) | ||
Unsteadiness when standing | 375 (25) | 355 (24) |
Blurred vision when standing | 85 (6) | 103 (7) |
Dizziness when standing | 324 (22) | 304 (20) |
Light-headedness when standing | 222 (15) | 236 (16) |
Palpitations when standing | 21 (0.2) | 24 (0.2) |
Abbreviations: BP, blood pressure; DBP, diastolic blood pressure; SBP, systolic blood pressure.
* Difference between higher and lower groups is significant at P < 0.001.
** Difference between higher and lower groups is significant at P < 0.0001.