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. Author manuscript; available in PMC: 2015 Feb 1.
Published in final edited form as: Biochim Biophys Acta. 2013 Jun 6;1840(2):847–875. doi: 10.1016/j.bbagen.2013.05.040

Scheme 3.

Scheme 3

Sulfenic acid mediated generation of 3-isothiazolidinone heterocycle which serves as a chemical model to understand the redox-regulation of PTP1B activity.