. Author manuscript; available in PMC: 2015 Feb 1.

Published in final edited form as: Biochim Biophys Acta. 2013 Jun 6;1840(2):847–875. doi: 10.1016/j.bbagen.2013.05.040

Table 2.

Second order rate constants and conditions for ONOO⁻ mediated oxidation of some biological small molecule thiols.^a

Thiol	pK_a	Rate constant (M⁻¹ s⁻¹)	Conditions
Penicillamine	7.9	6420	37 °C, pH 7.4
Cysteine	8.3	4500	37 °C, pH 7.4
Glutathione	8.8	1360	37 °C, pH 7.4
Homocysteine	9.1	700	37 °C, pH 7.4
N-Acetylcysteine	9.5	415	37 °C, pH 7.4

Values taken from reference [99].