Table 4.
Clinical characteristics and results of laboratory investigations of the six patients with a positive Coxiella PCR
| Patient no. | Age | Sex | Clinical presentation | Laboratory findings | Sample | Coxiella burnetii PCR DNA copies/mL (mean value Ct) | Serology* |
|---|---|---|---|---|---|---|---|
| 1 | 65 | M | Aortic prosthesis infection Ileofemoral abscess | Serum and EDTA-blood negative by C. burnetii PCR | Femoro-iliac abscess | 260 (35.3) | Ph1: IgG: 6 400; IgM: 0; IgA: 3 200 |
| Aortic stent 1 | 19 900 (29.7) | Ph2: IgG: 6 400; IgM: 0; IgA: 800 | |||||
| Aortic stent 2 | 184 000 (26.1) | ||||||
| Inguinal fragment 1 | 124 (37.9) | ||||||
| Inguinal fragment 2 | 3100 (33.0) | ||||||
| Intraoperative groin biopsy | 123 (36.6) | ||||||
| 2 | 71 | F | Endocarditis | Periaortic valve abscess | 3500 (32.3) | Not available | |
| Pus around aortic valve | 1 357 900 (24.7) | ||||||
| 3 | 43 | F | Endocarditis | Eubacterial PCR positive for C. burnetii | Aortic valve | 1 000 000 (16.7) | Ph1: IgG: 6400; IgM: 0; IgA: 200 |
| Serum negative by C. burnetii PCR | Ph2: IgG: 12 800; IgM: 0; IgA: 400 | ||||||
| 4 | 53 | H | Aortic aneurysm | Pseudoaneurysm fragment | 380 (36.0) | Not available | |
| 5 | 57 | M | Spondylodiscitis | Paraffin-embedded tissue was also positive by PCR | L3–L4 vertebral biopsy | 18 969 (31.2) | Ph1: IgG: 8192; IgM: 0; IgA: 0 |
| Ph2: IgG: 4096; IgM: 0; IgA: 0 | |||||||
| 6 | 47 | M | Granulomatous hepatitis | Serum** | 390 (35) | **Ph1: IgG: 0; IgM: 0; IgA: 0 | |
| Ph2: IgG: >640; IgM: 0; IgA:0 |
*
Only highest titres are shown.
**
Serology on initial serum was negative for C. burnetii. The PCR was only positive on first serum