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. 2014 Feb 25;1(3):220–232. doi: 10.1002/acn3.41

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© 2014 The Authors. Annals of Clinical and Translational Neurology published by Wiley Periodicals, Inc on behalf of American Neurological Association.

This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Comparison of cognitive functioning over time between UIA patients and the general population. (A) The long-term presence of vascular risk factors results in pathological changes in cerebral vasculature, which in turn results in damage to white matter and this results in a decline in cognitive functioning. (B) UIA treatment results in a transient decline in cognitive functioning. Although cognitive functioning returns to pretreatment levels, it remains below that of the general population.