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Effects of sertraline and LF-3-88 in mice on total time immobile in the FST (A, i.p.; B, p.o.). Data were summed over the 6-min test and represent mean ± SEM. *P < 0.05 and **P < 0.001 indicates statistical significance compared with water. ANOVAs: (A) F(5, 54) = 9.0, P < 0.001; (B) F(4, 43) = 78.3, P < 0.001. FST, forced swim test.
