Table 1.

Doses (μg) of intrathecally injected opiates and NMDA receptor antagonists.

	Test
	Acute/heat	CCI/heat	CCI/tactile	Formalin
Opiates
Morphine	1, 3, 10	0.3, 1, 3, 10	0.1, 0.3, 1, 3	0.3, 1, 3
EM-1	3, 10, 30	1, 3, 10, 30	3, 10, 30	3, 10, 30
EM-2	20	3, 10, 30	2.5, 3, 8, 10, 25 30	1, 2.5, 3, 8, 10, 25, 30
NMDA receptor antagonists
Ketamine	10	10	10	10
SHG	1	0.3	0.3	0.3

CCI, chronic constriction injury; EM-1, endomorphin-1; EM-2, endomorphin-2; NMDA, N-methyl-d-aspartate; SHG, [Ser¹]histogranin.