Table 2. fMRI results for main effect of relationship (own vs. unfamiliar) in brain regions of interest.

ROI Analysis	Neurosyntha	Hemb	Clusterc	xd	yd	zd	F	p, FWE correctede
Amygdala	Emotion	L	90	−24	2	−16	16.48	0.017
Fusiform Gyrus	Semantic	L	228	−50	−64	−18	16.08	0.009
	Face	R	254	50	−60	−16	28.73	0.006
Insula	Sensory/Image	L	193	−32	14	2	24.30	0.016
PAG	N/A	L	12	−2	−32	−22	12.89	0.035
SNi/VTA	Reward	L	19	−2	−16	−16	23.72	0.028
	Reward	R	18	2	−16	−16	17.22	0.029
STG	Emotion	L	359	−38	10	−12	26.11	0.003
Thalamus	Motor/Sensory	L	219	−10	−14	6	13.47	0.005
	Motor	R	235	6	−20	6	13.25	0.004

^aNeurosynth term/function (www.neurosynth.org); N/A  =  not available in the Neurosynth atlas.

^bHemisphere: R, right, L, left

^cCluster size; number of contiguous voxels with p< 0.01.

^dx, y, and z coordinates in MNI space.

^eFamilywise error corrected at the cluster level.

All results significant at p< .05, cluster-level family-wise error correction.

Follow-up t-tests revealed all significant main effects were the result of greater brain activation in the own vs. unfamiliar (own > unfamiliar) contrast. There were no significant differences in ROI activation for the unfamiliar > own contrast.