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. 2014 Oct 3;9(10):e108107. doi: 10.1371/journal.pone.0108107

Figure 1. Consort diagram.

Figure 1

Showing the details of patients with central nervous system (CNS) relapse. c-CNS = combined bone marrow and CNS relapse; i-CNS = isolated CNS relapse; TRM = treatment related mortality; SCT = allogenic bone marrow transplant; CRT = chemo-radiotherapy. *1 patient planned for SCT received CRT and vice-versa; #9 patients planned for SCT received CRT; +9 patients planned for SCT received CRT and 2 patients planned for CRT got SCT. No patients with i-CNS had detectable MRD in the marrow at the end of induction. Twenty four patients with c-CNS has detectable marrow disease at week 5; 13 MRD positive and 9 MRD negative.