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. 2014 Oct 3;9(10):e108107. doi: 10.1371/journal.pone.0108107

Table 5. Characteristics of patients aged younger than 10, or 10 and older with CNS relapses.

Age at Relapse (years) <10 ≥10
n 78 45
CNS relapse (%)
Isolated 53 (68) 27 (60)
Combined 25 (32) 18 (40)
Gender
Male: Female 51∶27 37∶8
Time to Relapse (%)
median in months (range) 29 (5–92) 33 (6–90)
Late 18 (23) 14 (31)
Early 48 (62) 23 (51)
Very Early 12 (15) 8 (18)
Risk category
Standard 4 (5) 8 (18)
Intermediate 63 (81) 25 (55)
High 11 (14) 12 (27)
Immunophenotype
B:T 66∶12 31∶14
Cytogenetics (%)
progenitor-B cell
Good 32 (41) 11 (24)
Intermediate 18 (23) 11 (24)
Poor 5 (6) 6 (13)
Unknown 11 (14) 3 (7)
T-cell 12 (15) 14 (22)