Table 5. Characteristics of patients aged younger than 10, or 10 and older with CNS relapses.
Age at Relapse (years) | <10 | ≥10 |
n | 78 | 45 |
CNS relapse (%) | ||
Isolated | 53 (68) | 27 (60) |
Combined | 25 (32) | 18 (40) |
Gender | ||
Male: Female | 51∶27 | 37∶8 |
Time to Relapse (%) | ||
median in months (range) | 29 (5–92) | 33 (6–90) |
Late | 18 (23) | 14 (31) |
Early | 48 (62) | 23 (51) |
Very Early | 12 (15) | 8 (18) |
Risk category | ||
Standard | 4 (5) | 8 (18) |
Intermediate | 63 (81) | 25 (55) |
High | 11 (14) | 12 (27) |
Immunophenotype | ||
B:T | 66∶12 | 31∶14 |
Cytogenetics (%) | ||
progenitor-B cell | ||
Good | 32 (41) | 11 (24) |
Intermediate | 18 (23) | 11 (24) |
Poor | 5 (6) | 6 (13) |
Unknown | 11 (14) | 3 (7) |
T-cell | 12 (15) | 14 (22) |