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. 2014 Oct 3;9(10):e108415. doi: 10.1371/journal.pone.0108415

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© 2014 Phelan et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(Top) Schematic of secondary structures; loops (L), beta strands (B), and alpha helix (H) of darcin and MUP11. (Middle and Bottom) Plots of % of native backbone NH peaks observed at different urea concentrations for each secondary structure element in darcin (middle) and MUP11 (bottom); secondary structures are coloured coded as in the schematic. In darcin, the only region that is destabilised by urea is L8.