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. 2014 Oct 3;9(10):e108477. doi: 10.1371/journal.pone.0108477

Figure 4. Paricalcitol induced the recruitment of regulatory CD8+ T cells into the peritoneal cavity.

Figure 4

Paricalcitol (dashed box) tended to increase the frequency of CD4+ T cells expressing Foxp-3 (A), but not CTLA-4 (B) or membrane TGF-β (C). Paricalcitol increased the frequency of CD8+ T cells expressing Foxp-3 (A), CTLA-4 (B) and membrane TGF-β (C) compared with the PDF-group (white box). n≥9 in each group. Paricalcitol treated group had higher number of CD4+ CD8+ T cells expressing Foxp-3 than PDF group (D). Statistical significance was determined using the Mann-Whitney test. *P<.05; **P<.01; ***P<.001.