Table 4. The adjusted risks for rapid decline in renal function and change of eGFR according to Angiopoietin-2 quartile.

Angiopoietin-2a	Rapid decline in renal function		Change of eGFR
	Odds ratio (95% Cl)	P-value	Unstandardized coefficient βb (95% Cl)	P-value
Quartile 1	Reference		Reference
Quartile 2	3.40(1.32–8.75)	0.01	−1.03(−2.63,0.57)	0.1
Quartile 3	3.04(1.18–7.82)	0.02	−1.66(−3.25,−0.07)	0.03
Quartile 4	2.96(1.13–7.76)	0.02	−1.73(−3.33,−0.11)	0.03

Abbreviations: CI, Confidence Interval; eGFR, estimated glomerular filtration rate.

Adjusted model: age, sex, cardiovascular disease, diabetes mellitus, angiotensin converting enzyme inhibitors/angiotensin II receptor blockers use, estimated glomerular filtration rate, hemoglobin, serum calcium and cholesterol levels, log serum albumin and phosphate, , and urine protein-creatinine ratio cut at 1 g/g.

^aAngiopoietin-2 quartile cut at 1494.1, 1948.8, and 2593.1 pg/ml.

^bβ expressed as ml/min/1.73 m²/year in eGFR.