Table 3. Effect of ELAP on biochemical parameters in TAA-induced liver cirrhosis.
Treatment | Total protein (g/L) | Albumin (g/L) | Globulin (g/L) | Total bilirubin (µM) | Conjugated bilirubin (µM) |
Normal control | 68.67±1.4 | 12.83±0.70 | 54.5±0.22 | 2.7±0.21 | 1±0.00 |
TAA control | 60.83±0.47# | 7.83±0.16# | 68.66±1.4# | 9±0.21# | 5.3±0.00# |
Silymarin (50 mg/kg) | 67.33±0.95* | 11.83±0.74* | 54.33±1.47* | 5.6±0.76 | 3±0.36* # |
ELAP (250 mg/kg) | 61.5±0.67* # | 11.66±0.21* | 48±0.85* # | 7±0.36* # | 3.5±0.61* # |
ELAP (500 mg/kg) | 70±1.46* | 12.16±0.30* | 54.5±0.5* | 5±0.77* # | 3±0.22* # |
Data expressed as mean ± SEM (n = 6 rats/group).
*P<0.05 compared with TAA control,
P<0.05 compared with normal control.