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. 2014 Oct 3;9(10):e109649. doi: 10.1371/journal.pone.0109649

Table 2. Demographic data and clinical characteristics of total population, non-AKI and AKI groups according to ICU mortality.

Total Non-AKI group AKI group
Survival(n = 337) Non-survival(n = 206) p-value Survival(n = 266) Non-survival(n = 90) p-value Survival(n = 71) Non-survival(n = 116) p-value
Age (years) 62.8±0.9 62.1±1.0 NS (0.616) 60.4±1.7 62.1±1.0 NS (0.396) 65.8±1.8 62.9±1.4 NS (0.223)
Male/Female 218/82 172/71 NS (0.802) 194/72 66/24 NS (0.981) 52/19 78/38 NS (0.387)
Length of ICU stay (days) 8.4±0.6 15.8±0.9 <0.001 8.7±0.7 16.7±1.6 <0.001 12.3±1.3 14.6±1.3 NS (0.241)
Length of hospital stay (days) 23.4±1.2 19.2±1.2 0.016 22.5±1.3 17.3±1.6 0.012 34.3±2.9 14.7±1.3 <0.001
Body weight on ICU admission (kg) 63.3±0.8 61.0±0.9 NS (0.055) 63.9±0.9 59.5±1.4 0.011 60.8±1.5 61.7±1.3 NS (0.666)
GCS, ICU first day (points) 12.7±0.2 9.9±0.3 <0.001 12.7±0.3 10.8±0.5 0.001 11.9±0.5 8.9±0.5 <0.001
MAP, ICU admission (mmHg) 80.1±3.8 75.1±1.4 NS (0.170) 81.7±4.3 76.1±2.4 NS (0.370) 80.5±2.7 71.3±1.8 0.008
Serum creatinine, ICU first day (mg/dl) 1.7±0.1 2.5±0.1 <0.001 1.7±0.1 1.8±0.2 NS (0.444) 2.9±0.6 2.7±0.4 NS (0.765)
Arterial HCO3 , ICU first day 22.8±0.4 20.2±0.4 <0.001 23.1±0.4 22.1±0.7 NS (0.220) 20.6±0.8 18.5±0.6 0.021
Bilirubin, ICU first day (mg/dl) 1.8±0.2 7.4±0.7 <0.001 2.3±0.3 5.2±0.8 0.001 2.1±0.6 9.3±1.1 <0.001
Albumin, ICU first day (g/l) 3.1±0.1 2.5±0.1 <0.001 3.2±0.1 2.5±0.1 <0.001 2.6±0.6 2.4±0.4 0.014
Hemoglobin, ICU first day (g/dl) 11.1±0.2 9.6±0.1 <0.001 11.2±0.2 9.7±0.3 <0.001 10.2±0.3 9.4±0.2 0.022
Platelets, ICU first day (x103/µL) 186.8±6.1 141.7±7.4 <0.001 185.8±6.2 157.6±16.7 NS (0.077) 178.1±13.5 122.1±9.4 0.001
PaO2/FiO2, ICU first day (mmHg) 301.5±8.6 252.4±9.9 <0.001 308.2±9.3 233.9±16.7 <0.001 283.5±16.7 246.5±13.2 NS (0.086)
Score systems
APACHE II, ICU first day (mean ± SE) 14.5±0.4 23.8±0.5 <0.001 13.0±0.4 21.0±0.7 <0.001 19.1±0.8 25.9±0.7 <0.001
APACHE III, ICU first day (mean ± SE) 54.3±1.5 94.1±1.9 <0.001 54.5±1.6 82.2±2.9 <0.001 75.5±2.6 106.6±2.8 <0.001
SOFA, ICU first day (mean ± SE) 5.3±0.2 10.1±0.3 <0.001 5.0±0.2 8.2±0.4 <0.001 7.7±0.4 12.2±0.3 <0.001
RIFLE, ICU first day (mean ± SE) 0.5±0.1 1.4±0.1 <0.001 1.5±0.1 2.3±0.1 <0.001

Abbreviation: AKI, acute kidney injury; NS, not significant; ICU, intensive care unit; SE, standard error; GCS, Glasgow coma scale; MAP, mean arterial pressure; PaO2, arterial partial pressure of oxygen; FiO2, fraction of inspired oxygen; APACHE, Acute Physiology and Chronic Health Evaluation; SOFA, sequential organ failure assessment.