Table 4. Associations of GNAQ and GNA11 Mutations with Clinical-Pathologic Features of Uveal Melanoma in Chinese Patients.

Factors	Total n	GNAQ mut, n (%)	GNA11 mut, N (%)	WT, N (%)	P-Value	GNAQ/11 mut, N (%)	WT, N (%)	P-Value
	50 (100%)	9 (18%)	10 (20%)	31 (62%)		19 (38%)	31 (62%)
Gender
Men, n (%)	20 (40%)	6 (12%)	5 (10%)	9 (18%)	0.11	11 (22%)	9 (18%)	0.043
Women, n (%)	30 (60%)	3 (6%)	5 (10%)	22 (44%)		8 (16%)	22 (44%)
Age (Years)
Mean (range)	47.6 (23–78)	43.8 (32–58)	47.6 (25–68)	48.7 (23–78)	0.62	45.8 (25–68)	48.7 (23–78)	0.45
<50, n (%)	27 (54%)	7 (14%)	5 (10%)	15 (30%)	0.34	12 (24%)	15 (30%)	0.31
≥50, n (%)	23 (46%)	2 (4%)	5 (10%)	16 (32%)		7 (14%)	16 (32%)
Largest Basal Tumor Diameter (mm)
Mean (Range)	14.7 (6––20)	13.8 (9–20)	15.5 (7–20)	14.8 (6–20)	0.53	14.7 (7–20)	14.8 (6–20)	0.93
<16, n (%)	32 (64%)	7 (14%)	4 (8%)	21 (42%)	0.22	11 (22%)	21 (42%)	0.48
≥16, n (%)	18 (36%)	2 (4%)	6 (12%)	10 (20%)		8 (16%)	10 (20%)
Tumor Thickness (mm)
Mean (range)	9.5 (4–20)	9.6 (6–14)	10.7 (5–20)	9.1 (4–16)	0.39	10.2 (5–20)	9.1 (4–16)	0.26
<10, n (%)	26 (52%)	4 (8%)	4 (8%)	18 (36%)	0.61	8 (16%)	18 (36%)	0.27
≥10, n (%)	24 (48%)	5 (10%)	6 (12%)	13 (36%)		11 (22%)	13 (26%)
Epithelioid Cell Type
Yes, n (%)	8 (16%)	1 (2%)	3 (6%)	4 (8%)	0.54	4 (8%)	4 (8%)	0.72
No, n (%)	42 (84%)	8 (16%)	7 (14%)	27 (54%)		15 (30%)	27 (54%)
Scleral Invasion
Yes, n (%)	32 (64%)	4 (8%)	7 (14%)	21 (42%)	0.41	11 (22%)	21 (42%)	0.48
No, n (%)	18 (36%)	5 (10%)	3 (6%)	10 (20%)		8 (16%)	10 (20%)
Ciliary Body Involvement
Yes, n (%)	9 (18%)	0 (0%)	3 (6%)	6 (12%)	0.25	3 (6%)	6 (12%)	1.00
No, n (%)	41 (82%)	9 (18%)	7 (14%)	25 (50%)		16 (32%)	25 (50%)
Optic Disc Involvement
Yes, n (%)	12 (24%)	4 (8%)	4 (8%)	4 (8%)	0.045	8 (16%)	4 (8%)	0.045
No, n (%)	38 (76%)	5 (10%)	6 (12%)	27 (54%)		11 (22%)	27 (54%)