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. Author manuscript; available in PMC: 2015 Apr 1.
Published in final edited form as: Cancer Discov. 2014 Jul 11;4(10):1168–1181. doi: 10.1158/2159-8290.CD-13-0747

Figure 4.

Figure 4

Knockdown of FGFR signaling repressors transforms immortalized HBECs. A, Soft agar assay measuring colony formation of SA cells expressing FGFR1 relative to that obtained with empty vector, which was set to 1. Data are represented as mean ± SD. B, Tumor formation 6 weeks following injection of SA cells expressing FGFR1 or empty vector. C, Soft agar assay measuring colony formation of SA knockdown cell lines relative to that obtained with the non-silencing (NS) shRNA, which was set to 1. Data are represented as mean ± SD. D, Tumor formation in mice injected with SA knockdown cell lines; tumors were photographed at various time points following injection. *P<0.05; **P<0.01.