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. Author manuscript; available in PMC: 2015 Oct 1.
Published in final edited form as: Anal Bioanal Chem. 2014 Aug 29;406(26):6455–6468. doi: 10.1007/s00216-014-8067-2

Fig. 6.

Fig. 6

Proposed biodegradation pathways of CoA. CoA is depicted at the top. Enzymatic hydrolysis occurs at the bonds indicated by green dashed lines. Note that potential pathB involves an ectonucleotide pyrophosphatase. PathC also involves an ectoenzyme, pantotheinase. Reprinted with permission from Wu et al. (2013) Integrated Electroosmotic Perfusion of Tissue with Online Microfluidic Analysis to Track the Metabolism of Cystamine, Pantethine, and Coenzyme A. Analytical Chemistry 85 (24):12020–12027. Copyright 2013 American Chemical Society Electroosmotic perfusion of tissue