Table 3.
Correlates of Symptom Severity During Radiation Therapy for Head and Neck Cancer: Results of Multivariate Analyses and Model Comparison
| Covariate | Coefficient | 95% CI | P Value | Model AIC |
|---|---|---|---|---|
| Model With Baseline MDASI-HN in Covariate Pool | ||||
| Baseline MDASI-HN | 0.553 | 0.328 to 0.777 | <0.001 | 1442.5 |
| Concurrent chemo | 18.778 | 5.557 to32.000 | 0.006 | |
| Primary tumor site | 5.030 | 0.945 to 9.114 | 0.016 | |
| RT intent | 15.013 | 0.380 to 29.646 | 0.044 | |
| Model Without Baseline MDASI-HN in Covariate Pool | ||||
| ECOG PS | 46.040 | 15.655 to 76.426 | 0.003 | 1459.9 |
| Concurrent chemo | 25.364 | 45.752 to 64.218 | <0.001 | |
Abbreviations: CI, confidence interval; AIC, Aikake information criterion; ECOG PS, Eastern Cooperative Oncology Group performance status; MDASI-HN, MD Anderson Symptom Inventory–Head and Neck Module