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. Author manuscript; available in PMC: 2015 Oct 1.
Published in final edited form as: Clin Cancer Res. 2014 Apr 8;20(19):5064–5074. doi: 10.1158/1078-0432.CCR-13-3271

Table 1.

Characteristics of 68 pre-treatment tumor specimens derived from 41 patients receiving anti-PD-1 therapy.

Characteristic No. of Patients
(N=41)

Patient response to treatment
  Complete 2
  Partial 8
  Stable disease ≥6 months 2
  No response 29
Patient diagnosis
  Melanoma 16
  Non-small cell lung cancera 12
  Kidney cancer 6
  Colorectal cancer 5
  Castration-resistant prostate cancer 2
No. tumor specimens analyzed per patient
  1 25
  2 9
  3 5
  4 0
  5 2

No. of Specimens (N=68)

Primary vs. metastatic tumor
  Primary 29
  Metastasis 39
Anatomic location
  lymph node (metastasis) 17
  lung (primary or metastasis) 15
  other 36
a

Twelve cases include 9 adenocarcinomas and 3 squamous cell carcinomas of the lung.