Figure 3.
Association between obesity and HLA-DQ genotypes among 5 969 2–4 year old children genetically at risk for type 1 diabetes. Reference group = DQ2/8. Birth weight Z score was created to adjust for country, sex, mother’s height, gestational age and the number of fetuses in the pregnancy (singleton, twin, triplet, etc.) The development of persistent confirmed islet autoantibody and type 1 diabetes diagnosis was also adjusted for in the logistic regression model.