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Additive effects on maximum BMI in American Indian adults (a) and maximum BMI z score in children (b) with increasing numbers of risk alleles of rs74861148 and rs483154. Only 3.3 % subjects carried non-risk alleles at both loci (#risk allele = 0), thus these subjects were combined with those who carried one risk allele from either locus (#risk allele = 1). Maximum BMI values (mean ± SE), allelic effects (95 % CI) and p values were adjusted for age, sex, birth year and heritage
