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a Haplotype effects of rs74861148 and rs483154 on the lifetime BMI trajectory (age 5–50 years). b Haplotype effects of rs74861148 and rs483154 on the rate of BMI change in American Indian children and adults. The risk haplotype carriers (at least one copy) were compared with the non-risk haplotype carriers (no copies). BMI is given as an unadjusted mean at each age group. Rates of BMI change (mean ± SE), beta (95 % CI) and p values were adjusted for sex, birth year and heritage
