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. Author manuscript; available in PMC: 2015 Jul 15.
Published in final edited form as: Synthesis (Stuttg). 2014 Jul 15;46(14):1938–1946. doi: 10.1055/s-0033-1339128

Scheme 5.

Scheme 5

Copper-catalyzed decarboxylative trifluoromethylation of secondary propargyl bromodifluoroacetates displays atypical reactivity. The ratio of products represents an average of multiple runs