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Effect of magnetic particles on the fibrillogenesis of amyloid. Schematic representation of the possible scenario of a reduction in the toxic effects of Aβ. (A) Usual sequence from peptide to fibrils. (B) Peptide monomers are adsorbed onto the surface of SPIONs and the free peptide concentration is thus lowered; consequently, the possibility of forming oligomers and fibrils is also reduced.
