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. Author manuscript; available in PMC: 2015 Oct 15.
Published in final edited form as: J Immunol. 2014 Sep 12;193(8):4117–4124. doi: 10.4049/jimmunol.1401597

Figure 1. Priming with al-UV-DENV2 induces non-neutralizing DENV-specific IgG.

Figure 1

AG129 mice were primed with al-UV-DENV2 on days −14 and −5. On day −1, DENV-specific IgG levels were measured in the serum by ELISA (A) and the presence of neutralizing Abs was detected by PRNT50 (B).

Results were pooled from 2 independent experiments, n=9–10 total per group. The dotted line represents the background signal in A, and the detection limit in B. For B: each symbol represents one mouse, and the DENV-neutralizing Ab 4G2 was used as a positive control. Samples under the detection limit are represented in grey.