Skip to main content
. Author manuscript; available in PMC: 2014 Oct 5.
Published in final edited form as: Matrix Biol. 2014 Jul 4;0:48–58. doi: 10.1016/j.matbio.2014.06.005

Fig. 4. WDR72 immunolocalizes to vesicle-like puncta in Wdr72+/+ maturation-stage ameloblasts and shows protein-level knockout in Wdr72−/− mice.

Fig. 4

Representative sagittal sections of P10 male Wdr72+/+ and Wdr72−/− mandibles immunostained with a polyclonal rabbit antibody to WDR72 peptide. (A) In Wdr72+/+ mice, immunoreactivity (red) was diffusely positive in secretory ameloblasts and increased upon entry into the maturation stage (C, E), immunolocalizing to vesicle-like structures at the basal and apical ends (arrowheads). (B, D, F) Slight non-specific background immunoreactivity was present in Wdr72−/− ameloblasts. am, ameloblast; es, enamel space; pl, papillary layer; tp, Tomes' process. Scale bar, 10 μm.