Figure 3.

A schematic demonstrating the procedure to co-register pathology to T₂w MRI using LATIS. First, the source (1a) and target (1b) images are segmented, scaled and translated. Second, the prostate capsule and internal structure masks are identified to constrain the pathology transformation. The source and target masks (2a and 2b) are registered and a transformation matrix is obtained. Third, the transformation matrix is applied (red arrow) to the pathology (3a) which places it in spatial correspondence to the T₂w MRI resulting in (3b). Lastly, applying the transformation matrix to each one of the annotated cancer regions (4a) places them in the spatial framework of the anatomic T₂w images (4b).