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. Author manuscript; available in PMC: 2015 Oct 15.
Published in final edited form as: J Immunol. 2014 Sep 8;193(8):4060–4071. doi: 10.4049/jimmunol.1400318

Figure 1. STAT1 signaling is required for control of pulmonary fungal burden and survival following inoculation with C. neoformans strain H99γ.

Figure 1

129S6/SvEv (WT) and STAT1 KO mice were given an intranasal inoculation with 1 × 104 CFU of C. neoformans strain H99γ. Mice were observed for up to 60 days for survival analysis (A) or pulmonary fungal burden was analyzed at days 7 and 10 post inoculation (B). Experiments are cumulative of 2 experiments using 5 mice per group per time point (A) or 2 experiments using 4 mice per group per time point (B). (**p < 0.001; ***p < 0.0001)