Table 1.
Subject characteristics and descriptive statistics.
| All | Control group (weight change < 3%) |
Weight-loss group (weight loss ≥ 10%) |
P-value** | |
|---|---|---|---|---|
| n | 127 (100%) | 65 (51.18%) | 62 (48.82%) | |
| Age (years)* | 55.15 ± 6.38 | 53.78 ± 4.57 | 56.09 ± 6.89 | 0.156 |
| Sex (females)* | 71 (55.91%) | 38 (58.46%) | 33 (53.23%) | 0.893 |
| Baseline BMI (kg/m2)* | 27.27 ± 3.16 | 24.38 ± 3.39 | 27.49 ± 2.98 | 0.0005 |
| 48-month BMI (kg/m2) | 23.05 ± 2.71 | 24.36 ± 3.34 | 23.07 ± 2.68 | 0.036 |
| BMI Change (kg/m2) | −2.22 ± 2.47 | −0.026 ± 0.464 | −4.35 ± 1.60 | <0.0001 |
| Percent BMI Change (%) | −7.68 ± 8.65 | −0.072 ± 1.90 | −15.704 ± 5.00 | <0.0001 |
| Baseline KL Score* | 0.053 | |||
| KL=0 | 79 (62%) | 45 (69%) | 34 (55%) | |
| KL=1 | 27 (21%) | 15 (23%) | 12 (19%) | |
| KL=2 | 21 (17%) | 5 (8%) | 16 (26%) | |
| Previous Right Knee Injury | 34 (27%) | 18 (28%) | 16 (26%) | 0.619 |
| Previous Right Knee Surgery | 11 (9%) | 3 (5%) | 8 (13%) | 0.103 |
| Frequent Knee Bending Activity |
91 (72%) | 47 (73%) | 44 (71%) | 0.759 |
| Family History (Knee Replacement) |
23 (18%) | 12 (19%) | 11 (18%) | 0.852 |
| Heberden’s Nodes | 35 (28%) | 20 (31%) | 15 (25%) | 0.442 |
| Knee Symptoms (Pain, aching, or stiffness, past 12 months) |
27 (21%) | 9 (14%) | 18 (29%) | 0.030 |
*
Logistic regression models used for statistical analysis were adjusted for age, gender, baseline BMI, and baseline KL score to account for differences between groups.
**
P-values <0.05 are in bold.