Table 2.
Change of Inflammatory Marker Levels per 1 SD Increment of SFAs
| CRP (mg/L) | IL-6 (pg/mL) | WBC (k/μL) | Inflammation | |||||
|---|---|---|---|---|---|---|---|---|
|
| ||||||||
| % Change (95% CI) | P | % Change (95% CI) | P | % Change (95% CI) | P | Beta (95% CI) | P | |
| Saturated Fatty Acids | ||||||||
| Age-sex adjustment* | 4 (−13, 24) | 0.68 | 4 (−5, 13) | 0.40 | 0.7 (−4, 5) | 0.76 | 0.08 (−0.03, 0.20) | 0.15 |
| Multivariable† | 35 (−1, 84) | 0.06 | 20 (0.03, 43) | 0.05 | 6 (−8, 22) | 0.42 | 0.24 (0.002, 0.48) | 0.05 |
| Palmitic Acid | ||||||||
| Age-sex adjustment* | −15 (−34, 8) | 0.18 | 4 (−4, 13) | 0.37 | −0.3 (−5, 5) | 0.91 | 0.07 (−0.07, 0.21) | 0.35 |
| Multivariable† | −2 (−17, 17) | 0.85 | 8 (−1, 18) | 0.10 | −4 (−18, 13) | 0.65 | 0.11 (−0.004, 0.23) | 0.06 |
| Stearic Acid | ||||||||
| Age-sex adjustment* | 7 (−9, 25) | 0.40 | 2 (−7, 11) | 0.66 | 1 (−4, 6) | 0.69 | 0.07 (−0.04, 0.19) | 0.21 |
| Multivariable† | 35 (1, 80) | 0.04 | 7 (−12, 31) | 0.50 | 10 (−4, 27) | 0.16 | 0.16 (−0.09, 0.40) | 0.21 |
Abbreviations: BMI: Body Mass Index, CRP: C-Reactive Protein, IL-6: Interleukin-6, WBC: White Blood Count, SFA: Saturated Fatty Acids, TFA: Trans-Fatty Acids, ω3FA: Omega-3 Fatty Acids.
*
N is 87, 92, 91, and 96 in CRP, IL-6, WBC, and Inflammation models, respectively.
†
N is 85, 89, 88, and 93 in CRP, IL-6, WBC, and Inflammation models, respectively. Additional adjustment included race, smoking, BMI, statin use, aspirin use, TFA, and ω3FA.