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. Author manuscript; available in PMC: 2015 Jun 15.
Published in final edited form as: J Immunol. 2014 May 7;192(12):5679–5686. doi: 10.4049/jimmunol.1302755

Figure 1. DC activation and IL-12 production in tm and tm24KO mice.

Figure 1

Tm and tm24KO mice were subjected to flow cytometric analysis. (A) Surface staining of peripheral blood CD11c+ single-positive populations gated against SSC. Data of one representative mouse from 3 pairs of mice is shown. Averages of 3 mice per group from PBMC (*=p<0.05) or splenic CD11c+ populations are shown. (B) Single-positive CD11c+ population is gated and surface staining for CD80, CD86, and CD40 populations are gated and represented as average of MFI for 3 pairs of mice, (*=p<0.05). (C) PBMC from tm or tm24KO mice CD11c+ single-positive populations were gated on and intracellular IL-12 production was assessed. Data are graphed as average MFI of n=3 mice per group, (*=p<0.05). (D) Serum level of IL-12p40 at 6 months averaged for 6 pairs of mice, (*=p<0.05).