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. Author manuscript; available in PMC: 2015 Apr 1.
Published in final edited form as: Nature. 2014 Oct 2;514(7520):59–64. doi: 10.1038/nature13786

Figure 4.

Figure 4

Functional capacity varies by microenvironment. a, Shannon diversity of functional pathways and taxonomy by site; P-value, Kruskal-Wallis test between microenvironments. Error bars: standard error of the mean. b, Microenvironments possess different core modules; ‘core’ = occurrence in > 2/3 of samples. Error bars show variation within a class of modules (full version in Extended Data) that may arise from a unique specialization for that microenvironment. c, PCA shows clustering by microenvironment, with strong separation of sebaceous, dry, and toenail modules. Heatmaps: left, loadings for the first two PCs; right, mean relative abundances for modules with the greatest variation by microenvironment. d, A module’s taxonomic origin can be imputed by Spearman correlation (ρ; adjusted P ≤ 2e-16) with P. acnes and M. restricta relative abundances. e, Presence of select antibiotic resistance gene families by individual and site.