Table 1. Determination of isotype and specificity of tetanus toxin specific monoclonal antibodies.
mAbs | Isotype | Toxoid | Toxin | Fragment C | Light chain | Affinity Constant |
---|---|---|---|---|---|---|
1F3E3 | IgG2a | + | + | + | − | 1.78 × 109 |
1F2C2 | IgG2a | + | + | + | − | 7.1 × 108 |
1F1E12 | IgG2a | + | + | + | − | 8.1 × 108 |
1F2C8 | IgG2a | + | + | + | − | 1.9 × 109 |
1F3C3 | IgG2a | + | + | − | + | 6.6 × 107 |
1F3B3 | IgG2a | + | + | − | + | 7.0 × 107 |
1F4E11 | IgG2b | + | + | + | + | 2.1 × 108 |
2C9B6 | IgG2a | + | + | + | − | 1.98 × 108 |
3B3D9 | IgG2b | + | + | + | − | 9.06 × 108 |
5E6B10 | IgG2a | + | + | − | − | 1.8 × 109 |
1E4D5 | IgG2b | + | + | + | − | 3.79 × 109 |