Table 3. Geometric mean ELISA pertussis antigen antibody concentrations (95% CI).
Study groups | Difference between 4CMenB+Para and 4CMenB (95% CI) | |||
---|---|---|---|---|
4CMenB | 4CMenB + Para | Men C | ||
Pertussis Toxoid | ||||
Post-3rd dose |
66 (60–72) n = 140 |
67 (61–74) n = 135 |
70 (63–78) n = 132 |
1.02 (0.89–1.16) |
Pre-booster |
11 (9.7–13) n = 119 |
11 (9.9–13) n = 115 |
10 8.8–12) n = 131 |
1.02 (0.85–1.23) |
Post-booster |
104 (92–119) n = 118 |
106 (94–121) n = 120 |
111 (97–127) n = 119 |
1.02 (0.85–1.23) |
Filamentous hemagglutinin | ||||
Post-3rd dose |
73 (66–81) n = 140 |
72 (65–80) n = 135 |
77 (69–86) n = 132 |
0.99 (0.85–1.14) |
Pre-booster |
23 (20–26) n = 119 |
23 (21–27) n = 115 |
23 (21–27) n = 131 |
1.02 (0.85–1.22) |
Post-booster |
197 (173–224) n = 118 |
209 (184–238) n = 120 |
224 (194–258) n = 119 |
1.06 (0.89–1.28) |
Pertactin | ||||
Post-3rd dose |
114 (97–133) n = 140 |
102 (87–120) n = 135 |
138 (122–156) n = 132 |
0.9 (0.72–1.13) |
Pre-booster |
16 (13–19) n = 119 |
15 (12–17) n = 115 |
18 (16–21) n = 131 |
0.92 (0.72–1.17) |
Post-booster |
193 (163–228) n = 118 |
174 (147–206) n = 120 |
275 (233–325) n = 119 |
0.9 (0.71–1.15) |