Table 12.
Genetic diversity parameters and probability of adherence of diplotype frequencies to Hardy–Weinberg equilibrium expectations (pHWE), considering whole HLA-G ha.plotypes.
| Population sample | Gene diversity | Private haplotypes | Haplotype diversity | Nucleotide diversity (%) | pHWE |
|---|---|---|---|---|---|
| Africa (2n = 362) | 0.2913 ± 0.1949 | 36 | 0.9417 ± 0.0054 | 0.7643 ± 0.3690 | 0.6582 ± 0.0137 |
| LWK (2n = 188) | 0.3108 ± 0.1888 | 24 | 0.9497 ± 0.0075 | 0.7815 ± 0.3781 | 0.7200 ± 0.0130 |
| YRI (2n = 174) | 0.3175 ± 0.1722 | 10 | 0.9118 ± 0.0121 | 0.7283 ± 0.3531 | 0.5892 ± 0.0134 |
| Europe (2n = 752) | 0.2663 ± 0.2162 | 33 | 0.8622 ± 0.0088 | 0.7399 ± 0.3570 | 0.8219 ± 0.0113 |
| CEU (2n = 170) | 0.3315 ± 0.1902 | 6 | 0.8210 ± 0.0231 | 0.7384 ± 0.3579 | 0.5821 ± 0.0133 |
| FIN (2n = 184) | 0.2940 ± 0.1828 | 17 | 0.8501 ± 0.0187 | 0.6679 ± 0.3243 | 0.4973 ± 0.0142 |
| GBR (2n = 174) | 0.3234 ± 0.2036 | 8 | 0.8679 ± 0.0168 | 0.7632 ± 0.3696 | 0.3129 ± 0.0126 |
| IBS (2n = 28) | 0.4330 ± 0.1566 | 0 | 0.8492 ± 0.0412 | 0.7737 ± 0.3867 | 0.6021 ± 0.0065 |
| TSI (2n = 196) | 0.3055 ± 0.2078 | 9 | 0.8883 ± 0.0141 | 0.7546 ± 0.3653 | 0.7044 ± 0.0125 |
| Asia (2n = 570) | 0.2675 ± 0.2013 | 41 | 0.8503 ± 0.0090 | 0.6782 ± 0.3280 | 0.6628 ± 0.0137 |
| CHB (2n = 192) | 0.3185 ± 0.1816 | 5 | 0.8560 ± 0.0141 | 0.7093 ± 0.3439 | 0.3700 ± 0.0131 |
| CHS (2n = 200) | 0.3362 ± 0.1953 | 19 | 0.8141 ± 0.0204 | 0.6898 ± 0.3345 | 0.6625 ± 0.0134 |
| JPT (2n = 178) | 0.2710 ± 0.1617 | 4 | 0.8468 ± 0.0141 | 0.5857 ± 0.2854 | 0.5297 ± 0.0136 |
| Admixed (2n = 468) | 0.2908 ± 0.1999 | 26 | 0.9332 ± 0.0059 | 0.7890 ± 0.3805 | 0.6699 ± 0.0136 |
| ASW (2n = 118) | 0.3253 ± 0.1908 | 6 | 0.9483 ± 0.0092 | 0.8108 ± 0.3933 | 0.7233 ± 0.0130 |
| CLM (2n = 116) | 0.3337 ± 0.1786 | 8 | 0.9237 ± 0.0113 | 0.7655 ± 0.3718 | 0.3765 ± 0.0131 |
| MXL (2n = 124) | 0.3508 ± 0.1774 | 3 | 0.9110 ± 0.0146 | 0.8045 ± 0.3902 | 0.6571 ± 0.0129 |
| PUR (2n = 110) | 0.3220 ± 0.1687 | 7 | 0.9296 ± 0.0140 | 0.7599 ± 0.3693 | 0.3774 ± 0.0134 |
| Total (2n = 2152) | 0.2345 ± 0.2149 | - | 0.9068 ± 0.0040 | 0.7548 ± 0.3637 | 0.9025 ± 0.0089 |
CEU, Utah residents with Northern and Western European ancestry; TSI, Toscani from Italy; GBR, British from England and Scotland; FIN, Finnish from Finland; IBS, Iberian populations from Spain; CHB, Han Chinese from Beijing; CHS, Han Chinese from South China; JPT, Japanese from Tokyo, Japan; YRI, Yoruba from Ibadan, Nigeria; LWK, Luhya from Webuye, Kenya; ASW, people of African ancestry from the southwestern United States; MXL, people of Mexican ancestry from Los Angeles, California; PUR, Puerto Ricans from Puerto Rico; CLM, Colombians from Medellin, Colombia.