Table 14.
Genetic diversity parameters and probability of adherence of diplotype frequencies to Hardy–Weinberg equilibrium expectations (pHWE), considering HLA-G coding region haplotypes.
| Population sample | Gene diversity | Private haplotypes | Haplotype diversity | Nucleotide diversity (%) | pHWE |
|---|---|---|---|---|---|
| Africa (2n = 362) | 0.2983 ± 0.2036 | 14 | 0.9177 ± 0.0053 | 0.6649 ± 0.3266 | 0.6983 ± 0.0122 |
| LWK (2n = 188) | 0.3100 ± 0.1981 | 9 | 0.9255 ± 0.0077 | 0.6691 ± 0.3295 | 0.6843 ± 0.0121 |
| YRI (2n = 174) | 0.3306 ± 0.1808 | 4 | 0.8934 ± 0.0116 | 0.6436 ± 0.3175 | 0.6841 ± 0.0110 |
| Europe (2n = 752) | 0.2588 ± 0.2233 | 15 | 0.8292 ± 0.0085 | 0.6229 ± 0.3063 | 0.6674 ± 0.0132 |
| CEU (2n = 170) | 0.3348 ± 0.1930 | 2 | 0.7908 ± 0.0221 | 0.6162 ± 0.3045 | 0.5567 ± 0.0117 |
| FIN (2n = 184) | 0.3019 ± 0.1893 | 8 | 0.8011 ± 0.0192 | 0.5665 ± 0.2808 | 0.5260 ± 0.0133 |
| GBR (2n = 174) | 0.3151 ± 0.2112 | 4 | 0.8449 ± 0.0163 | 0.6358 ± 0.3138 | 0.1818 ± 0.0096 |
| IBS (2n = 28) | 0.4308 ± 0.1625 | 0 | 0.8492 ± 0.0412 | 0.6405 ± 0.3262 | 0.5893 ± 0.0067 |
| TSI (2n = 196) | 0.3070 ± 0.2151 | 0 | 0.8563 ± 0.0136 | 0.6411 ± 0.3161 | 0.9138 ± 0.0062 |
| Asia (2n = 570) | 0.2631 ± 0.2097 | 13 | 0.7914 ± 0.0095 | 0.5772 ± 0.2848 | 0.4079 ± 0.0135 |
| CHB (2n = 192) | 0.3089 ± 0.1866 | 2 | 0.8106 ± 0.0144 | 0.5903 ± 0.2920 | 0.3012 ± 0.0107 |
| CHS (2n = 200) | 0.3567 ± 0.2013 | 8 | 0.7495 ± 0.0187 | 0.5934 ± 0.2934 | 0.4342 ± 0.0131 |
| JPT (2n = 178) | 0.2649 ± 0.1712 | 1 | 0.7645 ± 0.0188 | 0.4969 ± 0.2478 | 0.3456 ± 0.0110 |
| Admixed (2n = 468) | 0.2834 ± 0.2095 | 14 | 0.8970 ± 0.0060 | 0.6621 ± 0.3251 | 0.4418 ± 0.0136 |
| ASW (2n = 118) | 0.3200 ± 0.1953 | 3 | 0.9126 ± 0.0107 | 0.6796 ± 0.3355 | 0.4556 ± 0.0131 |
| CLM (2n = 116) | 0.3335 ± 0.1958 | 5 | 0.8888 ± 0.0127 | 0.6494 ± 0.3212 | 0.2857 ± 0.0113 |
| MXL (2n = 124) | 0.3482 ± 0.1815 | 2 | 0.8624 ± 0.0149 | 0.6655 ± 0.3287 | 0.9311 ± 0.0048 |
| PUR (2n = 110) | 0.3264 ± 0.1823 | 3 | 0.8992 ± 0.0138 | 0.6471 ± 0.3202 | 0.5820 ± 0.0123 |
| Total (2n = 2152) | 0.2244 ± 0.2219 | – | 0.8780 ± 0.0038 | 0.6432 ± 0.3156 | 0.5692 ± 0.0143 |
CEU, Utah residents with Northern and Western European ancestry; TSI, Toscani from Italy; GBR, British from England and Scotland; FIN, Finnish from Finland; IBS, Iberian populations from Spain; CHB, Han Chinese from Beijing; CHS, Han Chinese from South China; JPT, Japanese from Tokyo, Japan; YRI, Yoruba from Ibadan, Nigeria; LWK, Luhya from Webuye, Kenya; ASW, people of African ancestry from the southwestern United States; MXL, people of Mexican ancestry from Los Angeles, California; PUR, Puerto Ricans from Puerto Rico; CLM, Colombians from Medellin, Colombia.