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. 2014 Oct 6;2:42. doi: 10.3389/fbioe.2014.00042

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Copyright © 2014 Marchisio.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Eukaryotic repressilator. The repressilator scheme is drawn with eukaryotic Parts & Pools. Green straight lines represent transcription, blue ones, translation. mRNA maturation is modeled into each coding region where pre-mature mRNA interacts with the spliceosome. This requires a link between each transcription unit and the spliceosome Pool. Mature mRNA is exported into a Pool in the cytoplasm where translation takes place. Once synthesized, repressors are brought to their Pools in the nucleus from where they can flow to their target promoters and inhibit transcription.