Table 1.

Pharmacokinetic parameters determined for XG-102

Parameter	Definition
Cmax	Maximum measured concentration of the analyte in plasma
CL	Clearance
tmax	Time from dosing to maximum measured concentration
AUC0–∞	Area under the concentration-time curve of the analyte in plasma over the time interval from 0 extrapolated to infinity
AUC0–last	Area under the concentration-time curve of the analyte in plasma over the time interval from 0 up to the last quantifiable plasma concentration
%AUCextrap	Percentage of AUC0–∞ extrapolated beyond the last quantifiable plasma concentration
λz	Terminal rate constant in plasma
t½	Terminal half-life of the analyte in plasma
MRT	Mean residence time
Vss	Volume of distribution at steady state