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Correlation of the residue-specific chemical shift changes of (Ca2+)4-CaM upon titration with isoflurane and sevoflurane. Residue-specific Δδ (1H,15N), in Hz, for 0.2 mmol/L U-[13C,15N]-(Ca2+)4-CaM with 0/10 mmol/L sevoflurane versus Δδ (1H,15N), in Hz, for 0.1 mmol/L U-[15N]-(Ca2+)4-CaM with 0/13 mmol/L isoflurane, is shown as measured for 88 backbone amides.
