Table 1.

Definition of adverse drug reaction frequency intervals in Denmark and the USA

Frequency	European commission definition	Definition often observed in PIs from the USA	Frequency interval
≥1/10	Very common	Frequent	Higher frequency interval
≥1/100 to <1/10	Common	Frequent	Higher frequency interval
≥1/1000 to <1/100	Uncommon	Infrequent	Higher frequency interval
≥1/10,000 to <1/1000	Rare	Rare	Lower frequency interval
<1/10,000	Very rare	Rare	Lower frequency interval
Not estimated	Not known	Unknown	Lower frequency interval