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Dose-related inhibition of neutrophil recruitment by GS-5759 in the BAL of cigarette smoke-exposed C3H/HeN mice. Data represent the mean ± SEM neutrophil numbers in the BAL fluid following cigarette smoke exposure of mice over 18 days (n = 6–8). GSK, GSK256066; IND, indacaterol; CIS, ciclesonide. ***P < 0.001 compared to vehicle-treated and air-exposed mice, #P < 0.05 compared to vehicle-treated and smoke-exposed mice.
