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Effect of temperature on drug concentration in locust brain. Brain concentration of carbamazepine, quinidine, and quinidine + verapamil (30 μmol/L) after ex vivo exposure at a concentration of 3 μmol/L and at the temperatures 30°C or 2°C for 5 min. Data presented as mean ± SD, n = 3 samples in each group. (*P < 0.05, **P < 0.01, ***P < 0.001).
