Table 3.
Plasma cytokine profile in TRPA1 WT and TRPA1 KO mice following 14-day infusion of angiotensin II
| 14-day angiotensin II | ||
|---|---|---|
| TRPA1 WT | TRPA1 KO | |
| Plasma IL-1β (pg mL−1) | 2.858 ± 1.705 | 2.490 ± 1.600 |
| N = 18 | N = 17 | |
| Plasma TNFα (pg mL−1) | 9.458 ± 2.835 | 8.821 ± 3.144 |
| N = 18 | N = 17 | |
| Plasma IL-12 (pg mL−1) | 273.7 ± 436.3 | 124.5 ± 142.4 |
| N = 18 | N = 17 | |
| Plasma KC (pg mL−1) | 280.8 ± 275.9 | 326.7 ± 323.3 |
| N = 18 | N = 17 | |
| Plasma IFNγ (pg mL−1) | 10.13 ± 9.736 | 6.971 ± 5.535 |
| N = 18 | N = 17 | |
| Plasma IL-10 (pg mL−1) | 111.3 ± 91.30 | 76.98 ± 53.82 |
| N = 17 | N = 17 | |
Angiotensin II (1.1 mg kg−1 a day for 14 days) was infused via a subcutaneously implanted minipump. Blood was collected at termination and plasma extracted. Cytokines were measured using a multiplex ELISA. N as indicated, data shown ± SEM.