Table 3.
Differential expressed genes encoding membrane transporters between central airways and peripheral tissue
| P-value | ||
|---|---|---|
| Central > peripheral | ||
| 1 | SLC2A1 (GLUT 1) | 0.00001 |
| 2 | SLC28A3 (CNT3) | 0.0003 |
| 3 | SLC22A4 (OCTN1) | 0.0006 |
| 4 | SLC51A (OSTalpha) | 0.0009 |
| 5 | ABCA4 (ABCA4) | 0.0017 |
| 6 | SLC15A2 (PEPT2) | 0.0018 |
| 7 | ATP7B (Copper transporter) | 0.0030 |
| 8 | ABCB6 (ABCB6) | 0.0030 |
| 9 | ABCA5 (ABCA5) | 0.0031 |
| 10 | SLC31A1 (CTR1) | 0.0071 |
| 11 | SLC7A1 (CAT1) | 0.0087 |
| Peripheral > central | ||
| 1 | SLC47A1 (MATE1) | 0.0006 |
| 2 | SLCO4C1 (OATP4C1) | 0.0017 |
| 3 | SLCO2B1 (OATP2B1) | 0.0025 |
| 4 | ABCA3 (ABCA3) | 0.0039 |
| 5 | ABCC4 (MRP4) | 0.0092 |
The P-values are unadjusted P-values from two-sided tests in the linear mixed model. The set of genes correspond to a FDR < 0.5.