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IC50 value (μmol/L) of isobenzofuranone compounds on antimony sensitive and resistant promastigotes
| Compounds | Parasite name | IC50 (μmol/L) |
|---|---|---|
| JVPH3 | AG83 (SbS) | 5.40 ± 0.0014 |
| GE1(SbR) | 9.81 ± 0.0017 | |
| JVPH4 | AG83 (SbS) | 6.01 ± 0.0011 |
| GE1(SbR) | 11.54 ± 0.0012 |
The results shown are the means of three independent experiments and represent mean ± SD from three independent experiments.
