Table 5.

Markers of severity in patients with underlying disease subgroups compared with previously healthy children (odds ratio and confidence interval)

	Oxygen therapy	Mechanical ventilation	PICU admission
Respiratory diseases (n = 145)	2·99 (1·03–8·65)*(n = 121)	0·70 (0·26–1·87) (n = 13)	0·59 (0·24–1·44) (n = 19)
Cardiac diseases (n = 56)	2·94 (0·94–9·23) (n = 48)	3·00 (1·07–8·44)** (n = 13)	2·08 (0·82–5·30) (n = 16)
Neurologic diseases (n = 28)	2·34 (0·65–8·47) (n = 24)	2·56 (0·86–7·60) (n = 6)	1·70 (0·62–4·67) (n = 7)
Chromosomal defects (n = 17)	2·87 (0·54–15·36) (n = 15)	1·03 (0·26–4·12) (n = 3)	0·66 (0·17–2·58) (n = 3)
Immunocompromised (n = 15)	1·33 (0·33–5·41) (n = 12)	2·77 (0·71–10·72) (n = 4)	2·08 (0·60–7·25) (n = 5)
Inborn errors of metabolism (n = 8)	3·02 (0·16–54·72) (n = 6)	12·27 (2·11–71·47)*** (n = 3)	6·70 (1·18–38·04)† (n = 3)

PICU, pediatric intensive care unit.

Results in boldface are statistically significant.

^*P < 0·05,

^**P < 0·05,

^***P < 0·01,

^†P < 0·05.