Table IV.

Corrleation between the concentration of MIF in pre- and postoperative serum and saliva samples of oral squamous cell carcinoma and tumor characteristics.

		Preoperative serum MIF (ng/ml)				Postoperative serum MIF (ng/ml)				Preoperative saliva MIF (ng/ml)				Postoperative saliva MIF (ng/ml)
Variable	n	Range	Median	P-value	n	Range	Median	P-value	n	Range	Median	P-value	n	Range	Median	P-value
Lymph node involvement				0.023				0.922				0.468				0.347
No	28	20.9–129.5	55.5		22	15.1–118.5	32.8		27	42.7–1490.2	255.5		23	79.7–1015.5	261.4
Yes	20	17.7–104.6	37.8		14	23.2–74.8	33.2		19	32.5–1770.6	474.2		10	64.5–2046.8	236.3
Largest diameter of metastatic lymph node (cm)				0.545				0.072				0.327				0.425
≤1.5	10	17.7–59.6	35.8		5	29.5–74.8	35.2		10	76.4–1770.6	426.2		3	221.8–388.9	250.9
>1.5	10	17.7–104.6	40.1		9	23.2–41.5	28.2		9	32.5–960.3	474.2		7	64.5–2046.8	162.3
Lymph node index				0.025				0.338				0.447				0.174
≤3.5	12	17.7–59.6	26.7		7	24.0–74.8	34.6		12	49.1–1770.6	426.2		5	162.3–2046.8	250.9
>3.5	8	23.1–104.6	56.7		7	23.2–41.5	29.5		7	32.5–1013.2	474.2		5	64.5–278.4	122.1
Largest diameter of primary tumor (cm)				0.754				0.724				0.020				0.028
≤2.5	13	17.7–104.6	54.2		10	18.3–118.5	33.8		13	49.1–867.6	125.0		10	79.7–512.1	166.5
>2.5	35	17.7–129.5	48.6		26	15.2–78.1	32.8		33	32.5–1770.6	406.2		23	64.5–2046.8	278.4
General index				0.071				0.648				0.025				0.120
≤2.9	10	20.9–99.9	64.4		8	18.3–118.5	33.8		10	45.6–461.8	142.0		8	79.7–512.1	193.2
>2.9	38	17.7–129.5	46.1		28	15.1–78.1	32.8		36	32.5–1770.6	395.5		25	64.5–2046.8	261.6

Bold P-value indicates statistical significance. P-value obtained from nonparametric Mann-Whitney U test, unless specified otherwise. MIF, macrophage migration inhibitory factor.