Table 1.
Baseline characteristics of the Reasons for Geographic and Racial Differences in Stroke (REGARDS) Study population ≥75 years old by eGFR
| Participant Characteristics | eGFR, ml/min per 1.73 m2 | ||
|---|---|---|---|
| ≥60 | 45–59 | <45 | |
| n | 2616 | 606 | 335 |
| Age, yr | 79.0±3.7 | 80.2±4.2 | 80.6±4.2 |
| Women | 54.8 | 53.6 | 64.2 |
| Black | 33.3 | 32.3 | 38.5 |
| Less than a high school education | 15.5 | 20.1 | 21.5 |
| Household income <$20,000 | 21.1 | 20.5 | 30.5 |
| Geographic region | |||
| Stroke belt | 30.3 | 29.9 | 27.5 |
| Stroke buckle | 18.9 | 22.6 | 21.5 |
| Other region | 50.8 | 47.5 | 51.0 |
| Current smoker | 5.2 | 6.0 | 7.2 |
| Hypertension | 64.6 | 78.0 | 82.0 |
| Atrial fibrillation | 12.3 | 15.1 | 25.0 |
| Coronary heart disease | 25.0 | 35.4 | 35.9 |
| Stroke | 7.5 | 10.4 | 10.6 |
| Diabetes mellitus | 17.3 | 25.9 | 30.2 |
| Systolic BP (mmHg) | 131.2±17.4 | 131.9±18.0 | 129.7±17.2 |
| Diastolic BP (mmHg) | 74.5±9.4 | 73.4±9.8 | 71.5±10.0 |
| Waist circumference (cm) | 92.9±14.9 | 94.4±13.7 | 95.0±13.4 |
| HDL cholesterol (mg/dl) | 54.0±16.8 | 51.8±17.4 | 50.1±15.9 |
| Total cholesterol (mg/dl) | 185.9±39.0 | 181.7±39.4 | 180.0±37.8 |
| High-sensitivity C-reactive protein (mg/L) | 1.8 (0.9–4.2) | 2.0 (0.9–4.5) | 2.8 (1.3–6.1) |
| Cognitive impairment | 13.2 | 15.2 | 18.8 |
| Depressive symptoms | 9.8 | 9.7 | 9.0 |
| Exhaustion | 14.6 | 18.0 | 23.3 |
| Falls (≥2 within the past year) | 9.3 | 8.9 | 10.8 |
| Impaired mobility | 17.7 | 21.3 | 28.4 |
| Polypharmacy (≥10 medications) | 19.8 | 27.6 | 34.6 |
Numbers are percentages or means±SDs except for high-sensitivity C-reactive protein, which is medians (25th–75th quartiles).